CeMMEC13
A selective TAF1 second bromodomain inhibitor with IC50 of 2.1 uM; shows high selectivity for the TAF1 (2) bromodomain over BRD4 (1), BRD9, CREBBP, EP300 and TAF1 (2) bromodomains (IC50>10 uM) ; synergizes with (+) -JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.
Product Specifications
CAS Number
1790895-25-8
Product Name Alternative
CeMMEC 13
Purity
>98% (HPLC)
Solubility
DMSO: 62 mg/mL (184.3 mM) ; Ethanol: 6 mg/mL (17.83 mM) ; Water: <1 mg/mL (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C (C1=CC (N (C) C2=C1C=CC=C2) =O) NC3=CC=C (OCCO4) C4=C3
Molecular Formula
C19H16N2O4
Molecular Weight
336.3
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (2,3-dihydro-1,4-benzodioxin-6-yl) -1,2-dihydro-1-methyl-2-oxo-4-quinolinecarboxamide
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