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PD-151746

A potent, selective, cell-permeable Calpain inhibitor with Ki of 0.26 uM for m-calpain; displays 20-fold selectivity over m-calpain; attenuates the SLLVY-AMC hydrolysis induced by maitotoxin in SY5Y cells; decreases cytotoxicity induced by oxidized low-density lipoprotein (oxLDL) in HMEC-1 cells.

Product Specifications

CAS Number

179461-52-0

Product Name Alternative

PD151746 | PD-151746

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 37 mg/mL

Smiles

O=C (O) /C (S) =C/C1=CNC2=C1C=C (F) C=C2

Molecular Formula

C11H8FNO2S

Molecular Weight

237.2501

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2-Propenoic acid, 3- (5-fluoro-1H-indol-3-yl) -2-mercapto-

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