PD-151746
A potent, selective, cell-permeable Calpain inhibitor with Ki of 0.26 uM for m-calpain; displays 20-fold selectivity over m-calpain; attenuates the SLLVY-AMC hydrolysis induced by maitotoxin in SY5Y cells; decreases cytotoxicity induced by oxidized low-density lipoprotein (oxLDL) in HMEC-1 cells.
Product Specifications
CAS Number
179461-52-0
Product Name Alternative
PD151746 | PD-151746
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 37 mg/mL
Smiles
O=C (O) /C (S) =C/C1=CNC2=C1C=C (F) C=C2
Molecular Formula
C11H8FNO2S
Molecular Weight
237.2501
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-Propenoic acid, 3- (5-fluoro-1H-indol-3-yl) -2-mercapto-
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