Caspofungin acetate

A lipopeptide antifungal agent that works by inhibiting the enzyme 1,3-beta-glucan synthase and thereby disturbing the integrity of the fungal cell wall.Fungal Infection Approved (In Vitro) :Caspofungin diacetate (1-8 mg/kg; i.p.; daily, for 7 days) is able to penetrate the CNS in mice and achieve concentrations that result in the reduction of Candida burden in the brain.Caspofungin diacetate (0.41-41 μM; i.p.; for 5 weeks; male C57BL/6 mice) is a safe antifungal agent at vitreal concentrations of 0.41 to 4.1 μM in mice.