NSC23005 sodium
A novel specific, effective p18 (p18INK4C) inhibitor that can selectively promote HSCs expansion with EC50 of 5.21 nM; inhibits p18, and then activates CDK4/6, promotes HSCs expansion in both murine and human models; shows no activity in promoting the proliferation of leukemia cells, and no significant cytotoxicity toward 32D cells or HSCs.
Product Specifications
CAS Number
1796596-46-7
Product Name Alternative
NSC 23005 sodium | NSC-23005 sodium | p18-IN-40
Purity
>98% (HPLC)
Solubility
DMSO: 6.4 mg/mL (Need ultrasonic)
Smiles
C1CCC (CC1) NS (=O) (=O) C2=CC=C (C=C2) C (=O) [O-].[Na+]
Molecular Formula
C13H16NNaO4S
Molecular Weight
305.33
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzoic acid, 4-[ (cyclohexylamino) sulfonyl]-, sodium salt (1:1)
Available Sizes
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