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CHMFL-BMX-078

CHMFL-BMX-078 is a highly selective, potent, type II irreversible BMX kinase inhibitor with IC50 of 11 nM; displays a high selectivity profile (S score (1) = 0.01) against the 468 kinases/mutants in the KINOMEscan evaluation and achieved at least 40-fold selectivity over BTK kinase; CHMFL-BMX-078 is a useful pharmacological tool to elucidate the detailed mechanism of BMX mediated signaling pathways.

Product Specifications

CAS Number

1808288-51-8

Product Name Alternative

CHMFL-BMX-078 | CHMFL-BMX 078 | CHMFL BMX 078 | CHMFLBMX078

Field of Research

Cell Biology

Purity

>98% (HPLC)

Solubility

DMSO: Soluble (< 1 mg/ml refers to the product slightly soluble or insoluble)

Smiles

O=C (C1=CN=C (NC2=CC=C (C) C (NC (C=C) =O) =C2) N=C1NC) NC3=CC (NC (C4=CC (OC) =C (OC) C (OC) =C4) =O) =CC=C3C

Molecular Formula

C33H35N7O6

Molecular Weight

625.686

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2- ((3-Acrylamido-4-methylphenyl) amino) -N- (2-methyl-5- (3,4,5-trimethoxybenzamido) phenyl) -4- (methylamino) pyrimidine-5-carboxamide

Available Sizes

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