Jaceosidin
Jaceosidin (4'-Demethyleupatilin, Jaseocidin) is a trihydroxyflavone that exhibits anti-allergic, anti-inflammatory and apoptosis inducing activties; promotes angiogenesis via activation of VEGFR2/FAK/PI3K/AKT/NF-κB signaling pathways in endothelial cells; shows selective suppression of proliferation (IC50 = 82.1 μM in HSC-3 cells and 97.5 μM in Ca9.22 cells) and accumulation of cells at the sub-G1 stage of the cell cycle, induces apoptotic cell death and inhibits the Akt pathway in oral cancer cells.
Product Specifications
CAS Number
18085-97-7
Product Name Alternative
4'-Demethyleupatilin | Jaseocidin
Purity
>98% (HPLC)
Solubility
DMSO: Soluble (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C1C=C (C2=CC=C (O) C (OC) =C2) OC3=CC (O) =C (OC) C (O) =C13
Molecular Formula
C17H14O7
Molecular Weight
330.292
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
5,7-dihydroxy-2- (4-hydroxy-3-methoxyphenyl) -6-methoxychromen-4-one
Available Sizes
Frequently Asked Questions
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