Proflavine Hemisulfate
Proflavine Hemisulfate is a topical antiseptic by interchelating DNA, thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands. (In Vitro) :Proflavine (0.1-10 μM; 24 hours) inhibits the growth of Kir3.2-transformant cells and Kir3.2 activity in a concentration-dependent manner.Proflavine (300 μM) progressively reduces the current amplitude of Kir3.2 mutant to 27.7±4.3% of the control. (In Vivo) :Proflavine (0.1-10 μM; 24 hours) inhibits the growth of Kir3.2-transformant cells and Kir3.2 activity in a concentration-dependent manner.Proflavine (300 μM) progressively reduces the current amplitude of Kir3.2 mutant to 27.7±4.3% of the control.
Product Specifications
CAS Number
1811-28-5
Product Name Alternative
Proflavine hemisulfate | Proflavine hemisulphate | EINECS 217-320-3
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Water: 22 mg/mL (85.18 mM)
Smiles
C1=CC (=CC2=NC3=C (C=CC (=C3) [NH3+]) C=C21) N.C1=CC (=CC2=NC3=C (C=CC (=C3) [NH3+]) C=C21) N.[O-]S (=O) (=O) [O-]
Molecular Formula
C26H24N604S
Molecular Weight
516.57
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(6-aminoacridin-3-yl) azanium; sulfate
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