What is the catalog number for ARV-825?

The catalog number for ARV-825 is orb1225875.

What sizes are available for ARV-825?

ARV-825 is available in the following size(s): 200 mg, 500 mg, 1 g, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does ARV-825 come in?

ARV-825 is available in 8 different pack sizes.

ARV-825 is currently made to order / not held in immediate stock. Contact us for lead time.

ARV-825

ARV-825 is a hetero-bifunctional PROTAC (Proteolysis Targeting Chimera) that recruits BRD4 to the E3 ubiquitin ligase cereblon, leading to fast, efficient, and prolonged degradation of BRD4 via the proteasome; shows more significant and longer lasting c-MYC suppression than small molecule inhibitors (JQ1, OTX015) ; leads to a superior effect on BL cells proliferation suppression.Breast Cancer, Preclinical.

Product Specifications

CAS Number

1818885-28-7

Product Name Alternative

ARV 825 | ARV825

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

O=C (NC1=CC=C (OCCOCCOCCOCCNC2=CC=CC (C (N3C (CC4) C (NC4=O) =O) =O) =C2C3=O) C=C1) C[C@H]5C6=NN=C (C) N6C7=C (C (C) =C (C) S7) C (C8=CC=C (Cl) C=C8) =N5

Molecular Formula

C46H47ClN8O9S

Molecular Weight

923.4316

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2- ((S) -4- (4-chlorophenyl) -2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl) -N- (4- (2- (2- (2- (2- ((2- (2,6-dioxopiperidin-3-yl) -1,3-dioxoisoindolin-4-yl) amino) ethoxy) ethoxy) ethoxy) ethoxy) phenyl) acetamide