SB-225002
A potent, selective non-peptide CXCR2 antagonist with IC50 of 22 nM; displays >150-fold selectivity over CXCR1; potently inhibits human and rabbit neutrophil chemotaxis induced by both IL-8 and GROalpha in vitro; selectively blocks IL-8-induced neutrophil margination in rabbits.
Product Specifications
CAS Number
182498-32-4
Product Name Alternative
SB225002
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (NC1=CC=C ([N+] ([O-]) =O) C=C1O) NC2=CC=CC=C2Br
Molecular Formula
C13H10BrN3O4
Molecular Weight
352.1402
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Urea, N- (2-bromophenyl) -N'- (2-hydroxy-4-nitrophenyl) -
Available Sizes
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