BI-7273
A potent, selective and cell-permeable BRD9 bromodomain inhibitor with IC50 of 19 nM in Alpha assay; displays >5-fold selectiveity over BRD7, and >5,000-fold over BRD4-BD1, BRD4-BD2, and BRD2-BD1; blocks EOL-1 cell proliferation with EC50 of 1.4 uM, and displays antitumor activity in an AML xenograft model.
Product Specifications
CAS Number
1883429-21-7
Product Name Alternative
BI7273 | BI 7273
Purity
>98% (HPLC)
Solubility
DMSO: 10 mg/mL
Smiles
O=C1N (C) C=C (C2=CC (OC) =C (CN (C) C) C (OC) =C2) C3=CC=NC=C13
Molecular Formula
C20H23N3O3
Molecular Weight
353.4149
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2,7-Naphthyridin-1 (2H) -one, 4-[4-[ (dimethylamino) methyl]-3,5-dimethoxyphenyl]-2-methyl-
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