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BI-9564

BI-9564 (BI9564) is a potent, selective, cell-permeable and noncytotoxic BRD9 bromodomain inhibitor with IC50 of 75 nM, Kd of 5,000-fold over BRD4-BD1, BRD4-BD2, and BRD2-BD1; blocks EOL-1 cell proliferation with EC50 of 0.8 uM, and displays antitumor activity in an AML xenograft model.

Product Specifications

CAS Number

1883429-22-8

Product Name Alternative

BI 9564 | BI9564

Purity

>98% (HPLC)

Solubility

DMSO: 7.2 mg/mL (Need warming)

Smiles

O=C1N (C) C=C (C2=CC (OC) =C (CN (C) C) C=C2OC) C3=CC=NC=C13

Molecular Formula

C20H23N3O3

Molecular Weight

353.4149

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4- (4- ((dimethylamino) methyl) -2,5-dimethoxyphenyl) -2-methyl-2,7-naphthyridin-1 (2H) -one

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