BI-9564
BI-9564 (BI9564) is a potent, selective, cell-permeable and noncytotoxic BRD9 bromodomain inhibitor with IC50 of 75 nM, Kd of 5,000-fold over BRD4-BD1, BRD4-BD2, and BRD2-BD1; blocks EOL-1 cell proliferation with EC50 of 0.8 uM, and displays antitumor activity in an AML xenograft model.
Product Specifications
CAS Number
1883429-22-8
Product Name Alternative
BI 9564 | BI9564
Purity
>98% (HPLC)
Solubility
DMSO: 7.2 mg/mL (Need warming)
Smiles
O=C1N (C) C=C (C2=CC (OC) =C (CN (C) C) C=C2OC) C3=CC=NC=C13
Molecular Formula
C20H23N3O3
Molecular Weight
353.4149
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4- (4- ((dimethylamino) methyl) -2,5-dimethoxyphenyl) -2-methyl-2,7-naphthyridin-1 (2H) -one
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