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ML327

ML327 is a small molecule that restores E-cadherin expression through regulation of E-cadherin transcription, displays an In-Cell Western EC50 of 1.0 uM; is inactive (>30 uM) against all know epigenetic targets (HDACs, MMPs, Sirtuins, etc.) that increase E-cadherin expression, and clean in a Ricerca ancillary pharmacology panel; possesses favorable physiochemical properties, an excellent dystrophia myotonica protein kinase (DMPK) profile.

Product Specifications

CAS Number

1883510-31-3

Product Name Alternative

ML 327

Purity

>98% (HPLC)

Solubility

DMSO: 32 mg/mL (< 1 mg/ml refers to the product slightly soluble or insoluble)

Smiles

C1C=CNC (=O) C=1C (=O) NCCCNC (=O) C1=NOC (C2=CC=CC=C2) =C1

Molecular Formula

C19H18N4O4

Molecular Weight

366.377

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

N- (3- (2-Hydroxynicotinamido) propyl) -5-phenylisoxazole-3-carboxamide

Available Sizes

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