ZM-241385
ZM-241385 is a potent, non-xanthine A2A selective adenosine receptor antagonist with rat PC12 binding pIC50 of 9.52; shows low affinity for A3 (pIC50=3.82) ; antagonizes vasodilatation of the coronary bed produced by 2-CADO and CGS21680 with pA2 of 8.57 and 9.02, respectively, in guinea-pig isolated Langendorff hearts; selectively attenuates the mean arterial blood pressure response produced by exogenous adenosine in conscious spontaneously hypertensive rats (3-10 mg/kg, p.o.) .
Product Specifications
CAS Number
139180-30-6
Product Name Alternative
ZM-241385 | ZM 241385
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 30 mg/mL
Smiles
OC1=CC=C (CCNC2=NC3=NC (C4=CC=CO4) =NN3C (N) =N2) C=C1
Molecular Formula
C16H15N7O2
Molecular Weight
337.336
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Phenol, 4-[2-[[7-amino-2- (2-furanyl) [1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino]ethyl]-
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