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Bacitracin

Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synthesis. (In Vitro) :Bacitracin (64 μg/mL, 24 h) together with Colistin shows antibacterial activity against S. aureus BA01611.Bacitracin (64 μg/mL, 1 or 2 h) damages the cell surface to grape-like cell clusters, and the cell boundaries are faint and unclear. (In Vivo) :Bacitracin (0-100 mg/kg, intramuscular injection, daily for 12 consecutive days) shows anti-tumor efficacy in HCC model.

Product Specifications

CAS Number

1405-87-4

Product Name Alternative

Bacitracin

Purity

>98% (HPLC)

Solubility

Water: 100 mg/mL (70.98 mM) ; DMSO: 100 mg/mL (70.98 mM)

Smiles

O=C (O) CC[C@@H] (NC ([C@@H] (NC ([C@H]1N=C ([C@@H] (N) [C@@H] (C) CC) SC1) =O) CC (C) C) =O) C (N[C@@H] ([C@@H] (C) CC) C (N[C@@H]2C (N[C@H] (CCCN) C (N[C@@H] ([C@H] (CC) C) C (N[C@H] (CC3=CC=CC=C3) C (N[C@@H] (CC4=CN=CN4) C (N[C@H] (CC (O) =O) C (N[C@@H] (CC (N) =O) C (NCCCC2) =O) =O) =O) =O) =O) =O) =O) =O) =O

Molecular Formula

C66H103N17O16S

Molecular Weight

1422.73

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(4R) -4-[[ (2S) -2-[[ (4R) -2-[ (1S,2S) -1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[ (2S,3S) -1-[[ (3S,6R,9S,12R,15S,18R,21S) -3- (2-amino-2-oxoethyl) -18- (3-aminopropyl) -12-benzyl-15-[ (2S) -butan-2-yl]-6- (carboxymethyl) -9- (1H-imidazol-5-ylmethyl) -2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid

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