JNK-IN-8
JNK-IN-8 is a potent, selective, pan-JNK inhibitor with IC50 of 4.7 nM, 18.7 nM and 1 nM for JNK1, JNK2 and JNK3, respectively; exhibits exceptional selectivity based upon KinomeScan and enzymatic profiling; inhibits c-Jun phosphorylation in HeLa and A375 cells with EC50 of 486 nM and 338 nM, respectively.
Product Specifications
CAS Number
1410880-22-6
Product Name Alternative
JNK-IN-8 | c-Jun N-terminal Kinase Inhibitor XVI
Field of Research
Signal Transduction
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 35 mg/mL
Smiles
CN (C/C=C/C (NC1=CC=CC (C (NC2=CC=C (C (C) =C2) NC3=NC=CC (C4=CN=CC=C4) =N3) =O) =C1) =O) C
Molecular Formula
C29H29N7O2
Molecular Weight
507.6
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzamide, 3-[[4- (dimethylamino) -1-oxo-2-buten-1-yl]amino]-N-[3-methyl-4-[[4- (3-pyridinyl) -2-pyrimidinyl]amino]phenyl]-
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