HDAC8-IN-22d
HDAC8-IN-22d is a potent, selective HDAC8 inhibitor with IC50 of 27.2 nM, exhibits no activity against other HDACs and limited activity against HDAC1 and 3; shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5) ; exhibits cytotoxicity against human lung CL1-5 cells (IC50=7.0 uM) similar to that of SAHA yet without significant cytotoxicity for normal IMR-90 cells.
Product Specifications
CAS Number
1417997-93-3
Product Name Alternative
HDAC8-IN-1 | MDK-7933 | MDK 7933 | MDK7933
Field of Research
Epigenetics & Chromatin
Purity
>98% (HPLC)
Solubility
DMSO: 130 mg/mL (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
ONC (/C=C/C1=CC=C (C=C1C2=CC=C (C=C2) C3=CC=CC=C3) OC) =O
Molecular Formula
C22H19NO3
Molecular Weight
345.398
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(2E) -N-Hydroxy-3- (5-methoxy[1,1':4',1''-terphenyl]-2-yl) -2-propenamide
Available Sizes
Frequently Asked Questions
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