LMK-235
A selective HDAC5 and HDAC4 inhibitor with IC50 of 4.22 nM and 11.9 nM respectively; less potent for HDAC1/11/2/8; demonstrates activity against chemoresistant cancer cell lines in an MTT assay for cytotoxicity using human ovarian cancer cell lines A2780 and cisplatin resistant A2780CisR (IC50 =0.49 and 0.32 uM respectively) .
Product Specifications
CAS Number
1418033-25-6
Product Name Alternative
LMK 235 | LMK 235
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 30 mg/mL
Smiles
O=C (NOCCCCCC (NO) =O) C1=CC (C) =CC (C) =C1
Molecular Formula
C15H22N2O4
Molecular Weight
294.3462
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzamide, N-[[6- (hydroxyamino) -6-oxohexyl]oxy]-3,5-dimethyl-
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