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LMK-235

A selective HDAC5 and HDAC4 inhibitor with IC50 of 4.22 nM and 11.9 nM respectively; less potent for HDAC1/11/2/8; demonstrates activity against chemoresistant cancer cell lines in an MTT assay for cytotoxicity using human ovarian cancer cell lines A2780 and cisplatin resistant A2780CisR (IC50 =0.49 and 0.32 uM respectively) .

Product Specifications

CAS Number

1418033-25-6

Product Name Alternative

LMK 235 | LMK 235

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 30 mg/mL

Smiles

O=C (NOCCCCCC (NO) =O) C1=CC (C) =CC (C) =C1

Molecular Formula

C15H22N2O4

Molecular Weight

294.3462

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Benzamide, N-[[6- (hydroxyamino) -6-oxohexyl]oxy]-3,5-dimethyl-

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