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Adefovir dipivoxil

Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir.

Product Specifications

CAS Number

142340-99-6

Product Name Alternative

GS 840, GS-0840, Hepsera | Preveon.

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

Ethanol: 100 mg/mL (199.41 mM) ; DMSO: 100 mg/mL (199.41 mM)

Smiles

CC (C) (C) C (=O) OCOP (=O) (COCCN1C=NC2=C1N=CN=C2N) OCOC (=O) C (C) (C) C

Molecular Formula

C20H32N5O8P

Molecular Weight

501.47

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

[2- (6-aminopurin-9-yl) ethoxymethyl- (2,2-dimethylpropanoyloxymethoxy) phosphoryl]oxymethyl 2,2-dimethylpropanoate

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