UNC1999
UNC1999 is a potent, orally bioavailable and selective inhibitor of EZH2 and EZH1 with IC50 of 2 nM and 45 nM in cell-free assays, respectively, showing >1000-fold selectivity over a broad range of epigenetic and non-epigenetic targets.
Product Specifications
CAS Number
1431612-23-5
Product Name Alternative
UNC1999 | UNC 1999 | UNC-1999
Purity
>98% (HPLC)
Solubility
Ethanol: 100 mg/mL (175.51 mM) ; DMSO: 100 mg/mL (175.51 mM)
Smiles
O=C (NCC1=C (CCC) C=C (C) NC1=O) C2=C3C (N (C (C) C) N=C3) =CC (C4=CC=C (N5CCN (C (C) C) CC5) N=C4) =C2
Molecular Formula
C33H43N7O2
Molecular Weight
569.74
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1-isopropyl-6- (6- (4-isopropylpiperazin-1-yl) pyridin-3-yl) -N- ((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl) methyl) -1H-indazole-4-carboxamide
Available Sizes
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