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AM-2394

A potent, orally bioavailable Glucokinase (GK) activator with EC50 of 60 nM; increases the affinity of GK for glucose by 10-fold, exhibits moderate clearance and good oral bioavailability in multiple animal models; lowers glucose excursion in an ob/ob mouse model of diabetes.Diabetes Preclinical.

Product Specifications

CAS Number

1442684-77-6

Product Name Alternative

AM2394

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 30 mg/mL

Smiles

O=C (NC) NC1=CC (OC2=CC (C) =CN=C2) =C (C3=CC=C (OCC (C) (O) C) N=C3) C=N1

Molecular Formula

C22H25N5O4

Molecular Weight

423.465

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Urea, N-[6'- (2-hydroxy-2-methylpropoxy) -4-[ (5-methyl-3-pyridinyl) oxy][3,3'-bipyridin]-6-yl]-N'-methyl-

Available Sizes

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