AM-2394
A potent, orally bioavailable Glucokinase (GK) activator with EC50 of 60 nM; increases the affinity of GK for glucose by 10-fold, exhibits moderate clearance and good oral bioavailability in multiple animal models; lowers glucose excursion in an ob/ob mouse model of diabetes.Diabetes Preclinical.
Product Specifications
CAS Number
1442684-77-6
Product Name Alternative
AM2394
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 30 mg/mL
Smiles
O=C (NC) NC1=CC (OC2=CC (C) =CN=C2) =C (C3=CC=C (OCC (C) (O) C) N=C3) C=N1
Molecular Formula
C22H25N5O4
Molecular Weight
423.465
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Urea, N-[6'- (2-hydroxy-2-methylpropoxy) -4-[ (5-methyl-3-pyridinyl) oxy][3,3'-bipyridin]-6-yl]-N'-methyl-
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