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K-Ras G12C-IN-12

An allosteric inhibitor of oncogenic K-Ras (G12C) with EC50 of 0.32 uM in H1792 cells; relys on the mutant cysteine for binding and therefore do not affect the wild-type K-Ras.

Product Specifications

CAS Number

1469337-95-8

Product Name Alternative

MDK-7958 | MDK7958 | MDK 7958 | K-Ras (G12C) inhibitor 12

Field of Research

Signal Transduction

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 48 mg/mL

Smiles

C=CC (N1CCN (C (CNC2=CC (I) =C (Cl) C=C2O) =O) CC1) =O

Molecular Formula

C15H17ClIN3O3

Molecular Weight

449.6713

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2-Propen-1-one, 1-[4-[2-[ (4-chloro-2-hydroxy-5-iodophenyl) amino]acetyl]-1-piperazinyl]-

Available Sizes

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