K-Ras G12C-IN-12
An allosteric inhibitor of oncogenic K-Ras (G12C) with EC50 of 0.32 uM in H1792 cells; relys on the mutant cysteine for binding and therefore do not affect the wild-type K-Ras.
Product Specifications
CAS Number
1469337-95-8
Product Name Alternative
MDK-7958 | MDK7958 | MDK 7958 | K-Ras (G12C) inhibitor 12
Field of Research
Signal Transduction
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 48 mg/mL
Smiles
C=CC (N1CCN (C (CNC2=CC (I) =C (Cl) C=C2O) =O) CC1) =O
Molecular Formula
C15H17ClIN3O3
Molecular Weight
449.6713
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-Propen-1-one, 1-[4-[2-[ (4-chloro-2-hydroxy-5-iodophenyl) amino]acetyl]-1-piperazinyl]-
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