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Ivabradine hydrochloride

Ivabradine hydrochloride, a new If inhibitor with IC 50 of 2.9 μM, which is a pure heart rate lowering agent. (In Vitro) :Ivabradine hydrochloride (1, 10, 20 mg/kg; i.p.) shows anticonvulsant and neuroprotective action in mice.Ivabradine hydrochloride (5, 10, 20 mg/kg; p.o.; daily for 1 weeks) lowers heart rate in mice with enhanced sympathoadrenergic activities.

Product Specifications

CAS Number

148849-67-6

Product Name Alternative

S 16257

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

Ethanol: 101 mg/mL (199.98 mM) ; Water: 82 mg/mL (162.36 mM) ; DMSO: 101 mg/mL (199.98 mM)

Smiles

CN (CCCN1CCC2=CC (=C (C=C2CC1=O) OC) OC) C[C@H]3CC4=CC (=C (C=C34) OC) OC.Cl

Molecular Formula

C27H37ClN2O5

Molecular Weight

505.05

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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