KDU-691
KDU-691 is a potent, selective, orally active parasite PI4K inhibitor with IC50 of 1.5 nM for P. vivax PI4K (PvPI4K) ; shows IC50 of 58 nM, 36 nM and 196 nM against P. falciparum (Pf, boold stages), P. yoelii (Py, schizont) and P. cynomolgi (Pc, hypnozoites) respectively; shows fully protective effect against P. cynomolgi sporozoites in animal models.
Product Specifications
CAS Number
1513879-19-0
Product Name Alternative
KDU691
Purity
>98% (HPLC)
Solubility
DMSO : 150 mg/mL. 357.26 mM
Smiles
ClC1=CC=C (N (C (C2=CN3C (C=N2) =NC=C3C4=CC=C (C (NC) =O) C=C4) =O) C) C=C1
Molecular Formula
C22H18ClN5O2
Molecular Weight
419.864
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (4-Chlorophenyl) -N-methyl-3-[4-[ (methylamino) carbonyl]phenyl]imidazo[1,2-a]pyrazine-6-carboxamide
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog