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KDU-691

KDU-691 is a potent, selective, orally active parasite PI4K inhibitor with IC50 of 1.5 nM for P. vivax PI4K (PvPI4K) ; shows IC50 of 58 nM, 36 nM and 196 nM against P. falciparum (Pf, boold stages), P. yoelii (Py, schizont) and P. cynomolgi (Pc, hypnozoites) respectively; shows fully protective effect against P. cynomolgi sporozoites in animal models.

Product Specifications

CAS Number

1513879-19-0

Product Name Alternative

KDU691

Purity

>98% (HPLC)

Solubility

DMSO : 150 mg/mL. 357.26 mM

Smiles

ClC1=CC=C (N (C (C2=CN3C (C=N2) =NC=C3C4=CC=C (C (NC) =O) C=C4) =O) C) C=C1

Molecular Formula

C22H18ClN5O2

Molecular Weight

419.864

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

N- (4-Chlorophenyl) -N-methyl-3-[4-[ (methylamino) carbonyl]phenyl]imidazo[1,2-a]pyrazine-6-carboxamide

Available Sizes

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