Marimastat
A broad spectrum MMP inhibitor for MMP9/1/2/14/7 with IC50 of 3/5/6/9/13 nM, respectively.Lung Cancer Phase 3 Clinical (In Vitro) :Marimastat (BB2516) (1 μM) shows inhibition of vascular outgrowth, and selectively affects angiogenesis. (In Vivo) :Animals receiving chemoradiation + Marimastat (BB2516) (8.7 mg/kg) have statistically significant delayed growth, compared to animals receiving chemoradiation alone. Marimastat (BB2516) may work in combination with chemotherapy and radiation to inhibit tumor growth.
Product Specifications
CAS Number
154039-60-8
Product Name Alternative
BB-2516 | TA-2516
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 140 mg/mL
Smiles
O=C (N[C@@H] (C (C) (C) C) C (NC) =O) [C@H] (CC (C) C) [C@H] (O) C (NO) =O
Molecular Formula
C15H29N3O5
Molecular Weight
331.4079
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Butanediamide, N4-[ (1S) -2,2-dimethyl-1-[ (methylamino) carbonyl]propyl]-N1,2-dihydroxy-3- (2-methylpropyl) -, (2S,3R) -
Available Sizes
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