NV-128
NV-128 (LY-303511) is a novel isoflavone derivative that inhibits mTOR and promotes caspase-independent cell death; induce significant cell death in both paclitaxel-resistant and carboplatin-resistant EOC cells with GI50 of 1-5 ug/mL; significantly depresses mitochondrial function by decrease in ATP, Cox-I, and Cox-IV levels, and by increase in mitochondrial superoxide and hydrogen peroxide.
Product Specifications
CAS Number
154447-38-8
Product Name Alternative
NV 128 | NV128 | LY-303511 | LY 303511
Purity
>98% (HPLC)
Solubility
DMSO: 100 mM (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
C1CN (CCN1) C2=CC (=O) C3=C (O2) C (=CC=C3) C4=CC=CC=C4
Molecular Formula
C19H18N2O2
Molecular Weight
306.365
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- (1-Piperazinyl) -8-phenyl-4H-1-benzopyran-4-one
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