TP-0463518
TP-0463518 is a novel, highly potent HIF prolyl hydroxylase (PHD) inhibitor with IC50 of 13 nM and 18 nM for human and rat PHD2, respectively; demonstrates to promote the production of erythropoietin (EPO) following oral administration in mice and rats, shows potential for treatment of renal anemia.
Product Specifications
CAS Number
1558021-37-6
Product Name Alternative
TP0463518
Purity
>98% (HPLC)
Solubility
DMSO: 110 mg/mL (254.73 mM) (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
ClC (C=C1) =CC=C1OC2=NC=C (CN3C (C (C (NCC (O) =O) =O) =C (O) CC3) =O) C=C2
Molecular Formula
C20H18ClN3O6
Molecular Weight
431.829
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(1- ((6- (4-chlorophenoxy) pyridin-3-yl) methyl) -4-hydroxy-2-oxo-1,2,5,6-tetrahydropyridine-3-carbonyl) glycine
Available Sizes
Frequently Asked Questions
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