SGC0946
SGC0946 is a highly potent and selective DOT1L methyltransferase inhibitor with IC50 of 0.3 nM; selectively kill mixed lineage leukaemia cells.
Product Specifications
CAS Number
1561178-17-3
Product Name Alternative
SGC-0946 | SGC 0946 | SGC0946.
Purity
>98% (HPLC)
Solubility
Ethanol: 100 mg/mL (161.66 mM) ; DMSO: 100 mg/mL (161.66 mM)
Smiles
O=C (NC1=CC=C (CC (C) C) C=C1) NCCCN (C[C@H]2O[C@@H] (N3C=C (Br) C4=C (N) N=CN=C43) [C@H] (O) [C@@H]2O) C (C) C
Molecular Formula
C28H40BrN7O4
Molecular Weight
618.57
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1- (3- ((((2R,3S,4R,5R) -5- (4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl) -3,4-dihydroxytetrahydrofuran-2-yl) methyl) (isopropyl) amino) propyl) -3- (4-isobutylphenyl) urea
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