JNJ-632
JNJ-632 (JNJ632) is a novel potent HVV capsid assembly modulator and HBV replication inhibitor with EC50 of 100-200 nM for genotypes A-D; does not show cytotoxicity for HepG2 cells (CC50>100 uM) ; dose-dependently reduces intracellular HBV RNA levels as well as HBe/cAg and HBsAg levels in the cell culture supernatant.
Product Specifications
CAS Number
1572510-42-9
Product Name Alternative
JNJ632
Purity
>98% (HPLC)
Solubility
DMSO : 125 mg/mL330.32 mM
Smiles
O=C (NC1=CC=C (F) C (C) =C1) C2=CC=CC (S (=O) (N[C@@H]3COCC3) =O) =C2
Molecular Formula
C18H19FN2O4S
Molecular Weight
378.418
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(S) -N- (4-fluoro-3-methylphenyl) -3- (N- (tetrahydrofuran-3-yl) sulfamoyl) benzamide
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