NSC632839
A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases; induce a unique apoptotic pathway, which includes a Bcl-2-dependent but apoptosome-independent mitochondrial pathway with up-regulation of the BH3-only protein Noxa, stabilization of the IAP antagonist Smac, but also the involvement of the death receptor pathway.
Product Specifications
CAS Number
157654-67-6
Product Name Alternative
NSC-632839 | NSC 632839 | Ubiquitin Isopeptidase-IN-F6
Purity
>98% (HPLC)
Solubility
DMSO: 6.2 mg/mL (Need warming)
Smiles
CC1=CC=C (C=C1) C=C2CNCC (=CC3=CC=C (C=C3) C) C2=O.Cl
Molecular Formula
C21H22ClNO
Molecular Weight
339.8585
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-Piperidinone, 3,5-bis[ (4-methylphenyl) methylene]-, hydrochloride (1:1)
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