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NSC632839

A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases; induce a unique apoptotic pathway, which includes a Bcl-2-dependent but apoptosome-independent mitochondrial pathway with up-regulation of the BH3-only protein Noxa, stabilization of the IAP antagonist Smac, but also the involvement of the death receptor pathway.

Product Specifications

CAS Number

157654-67-6

Product Name Alternative

NSC-632839 | NSC 632839 | Ubiquitin Isopeptidase-IN-F6

Purity

>98% (HPLC)

Solubility

DMSO: 6.2 mg/mL (Need warming)

Smiles

CC1=CC=C (C=C1) C=C2CNCC (=CC3=CC=C (C=C3) C) C2=O.Cl

Molecular Formula

C21H22ClNO

Molecular Weight

339.8585

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4-Piperidinone, 3,5-bis[ (4-methylphenyl) methylene]-, hydrochloride (1:1)

Available Sizes

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