SCH-58261
SCH-58261 is a potent and selective, competitive A2A adenosine receptor antagonist with Ki of 2.3 nM and 2.0 nM in rat and bovine brain, respectively; displays 323-, 53- and 100-fold selectivity over A1, A2B and A3 receptors, respectively; reverses reperfusion injury (IR) increased hippocampal Glu, GABA, glycine and aspartate, MPO, TNF-α, nitric oxide, and PGE in Male Wistar rats.
Product Specifications
CAS Number
160098-96-4
Product Name Alternative
SCH 58261 | SCH58261
Field of Research
Signal Transduction
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 34 mg/mL
Smiles
NC1=NC (N (CCC2=CC=CC=C2) N=C3) =C3C4=NC (C5=CC=CO5) =NN14
Molecular Formula
C18H15N7O
Molecular Weight
345.358
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2- (2-furanyl) -7- (2-phenylethyl) -
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