Tucidinostat
Tucidinostat (Chidamide, HBI-8000, CS055) is a novel histone deacetylase (HDAC) inhibitor with IC50 of 95/160/67/733/78/432 nM for HDAC1/2/3/8/10/11, respectively; shows no activity against Class IIa HDAC4/4/7/9 and HDAC6; demonstrates significant and broad spectrum in vitro and in vivo antitumor activity, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells.Blood Cancer Approved.
Product Specifications
CAS Number
1616493-44-7
Product Name Alternative
Chidamide | HBI-8000 | CS055
Purity
>98% (HPLC)
Solubility
Ethanol: 1 mg/mL Water: InsolubleDMSO: 50 mg/mL (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C (NC1=CC=C (F) C=C1N) C2=CC=C (CNC (/C=C/C3=CC=CN=C3) =O) C=C2
Molecular Formula
C22H19FN4O2
Molecular Weight
390.418
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (2-amino-4-fluorophenyl) -4-[[[ (E) -3-pyridin-3-ylprop-2-enoyl]amino]methyl]benzamide
Available Sizes
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