Amentoflavone
Amentoflavone can interact with many other medications by being a potent inhibitor of CYP3A4 and CYP2C9, which are proteins used for drug metabolism in the body, is an inhibitor of human cathepsin B. It has antimalarial activity in trials significant affinities towards the delta-1, kappa opioid receptors (as an antagonist) and binds to benzodiazepine receptors. Amentoflavone may be a potential lead for a new type of anti-inflammatory agents having dual inhibitory activity of group II phospholipase A2 and cyclooxygenase. Amentoflavone and quercetin differentially exerted supression of PGE2 biosynthesis via downregulation of COX-2/iNOS expression.
Product Specifications
CAS Number
1617-53-4
Product Name Alternative
Didemethyl Ginkgetin | NSC 295677
Purity
>98% (HPLC)
Solubility
Soluble in Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone
Smiles
O=C1C=C (C2=CC=C (O) C=C2) OC3=C1C (O) =CC (O) =C3C4=CC (C5=CC (C6=C (O5) C=C (O) C=C6O) =O) =CC=C4O
Molecular Formula
C30H18O10
Molecular Weight
538.46
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
8-[5- (5,7-Dihydroxy-4-oxo-chromen-2-yl) -2-hydroxy-phenyl]-5,7-dihydroxy-2- (4-hydroxyphenyl) chromen-4-one
Available Sizes
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