Remodelin hydrobromide
A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules; significantly reduces the prevalence of misshapen nuclei in HGPS cells, prevents FTI-induced nuclear shape defects in normal fibroblasts and U2OS cells; does not affect Golgi apparatus integrity or tubulin polymer assembly, and does not cause cells to accumulate in mitosis.
Product Specifications
CAS Number
1622921-15-6
Product Name Alternative
Remodelin HBr | Remodelin Hydrobromide
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 44 mg/mL
Smiles
N#CC1=CC=C (C2=CSC (N/N=C3CCCC/3) =N2) C=C1.[H]Br
Molecular Formula
C15H15BrN4S
Molecular Weight
363.2754
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzonitrile, 4-[2- (2-cyclopentylidenehydrazinyl) -4-thiazolyl]-, hydrobromide (1:1)
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