MTX-211
A first-in-class, highly selective, dual inhibitor of PI3K and EGFR kinases with demonstrated in vivo anticancer activity against multiple KRAS mutant colorectal tumors; shows limited off-target toxicity and a broad therapeutic window.
Product Specifications
CAS Number
1952236-05-3
Product Name Alternative
MTX 211
Purity
>98% (HPLC)
Solubility
DMSO: ≥100 mg/mL (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
CS (=O) (NC1=CC (C2=CC3=C (NC4=CC=C (F) C (Cl) =C4) N=CN=C3C=C2) =CN=C1Cl) =O
Molecular Formula
C20H14Cl2FN5O2S
Molecular Weight
478.323
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Methanesulfonamide, N-[2-chloro-5-[4-[ (3-chloro-4-fluorophenyl) amino]-6-quinazolinyl]-3-pyridinyl]-
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