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MTX-211

A first-in-class, highly selective, dual inhibitor of PI3K and EGFR kinases with demonstrated in vivo anticancer activity against multiple KRAS mutant colorectal tumors; shows limited off-target toxicity and a broad therapeutic window.

Product Specifications

CAS Number

1952236-05-3

Product Name Alternative

MTX 211

Purity

>98% (HPLC)

Solubility

DMSO: ≥100 mg/mL (< 1 mg/ml refers to the product slightly soluble or insoluble)

Smiles

CS (=O) (NC1=CC (C2=CC3=C (NC4=CC=C (F) C (Cl) =C4) N=CN=C3C=C2) =CN=C1Cl) =O

Molecular Formula

C20H14Cl2FN5O2S

Molecular Weight

478.323

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Methanesulfonamide, N-[2-chloro-5-[4-[ (3-chloro-4-fluorophenyl) amino]-6-quinazolinyl]-3-pyridinyl]-

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