Piperlongumine
A naturally occurring small molecule recently identified to be toxic selectively to cancer cells in vitro and in vivo; elevates cellular levels of reactive oxygen species (ROS) selectively in cancer cell lines, potently inhibits the growth of spontaneously formed malignant breast tumours and their associated metastases in mice; inhibits the STAT3 signal pathway in MM cells by binding directly to the STAT3 Cys712 residue.
Product Specifications
CAS Number
20069-09-4
Product Name Alternative
Piplartine
Purity
>98% (HPLC)
Solubility
DMSO: 31.7 mg/mL (100 mM) (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C1C=CCCN1C (/C=C/C2=CC (OC) =C (OC) C (OC) =C2) =O
Molecular Formula
C17H19NO5
Molecular Weight
317.34
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
5,6-dihydro-1-[ (2E) -1-oxo-3- (3,4,5-trimethoxyphenyl) -2-propen-1-yl]-2 (1H) -pyridinone
Available Sizes
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