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BRD4 degrader AT1

BRD4 degrader AT1 is a highly selective BED4 degrader (PROTAC), exhibits highly selective depletion of BRD4 in cells with negligible activity against BRD2 and BRD3.

Product Specifications

CAS Number

2098836-45-2

Product Name Alternative

BRD4 PROTAC AT1

Field of Research

Epigenetics & Chromatin

Purity

>98% (HPLC)

Solubility

DMSO : 100 mg/mL 102.81 mM

Smiles

CC1=C (C2=CC=C (CNC ([C@H]3N (C ([C@@H] (NC (C) =O) C (C) (SCCCCCCNC (C[C@H]4C5=NN=C (C) N5C (SC (C) =C6C) =C6C (C7=CC=C (Cl) C=C7) =N4) =O) C) =O) C[C@H] (O) C3) =O) C=C2) SC=N1

Molecular Formula

C48H58ClN9O5S3

Molecular Weight

972.68

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(2S,4R) -1- ((R) -2-acetamido-3- ((6- (2- ((S) -4- (4-chlorophenyl) -2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl) acetamido) hexyl) thio) -3-methylbutanoyl) -4-hydroxy-N- (4- (4-methylthiazol-5-yl) benzyl) pyrrolidine-2-carboxamide

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