WHI-P97
A potent, specific JAK3 inhibitor with Ki of 0.6-2.3 uM; inhibits the translocation of 5-lipoxygenase (5-LO) from the nucleoplasm to the nuclear membrane and inhibits mast cell leukotriene synthesis in vitro; shows promising biological activity in mouse model of allergic asthma.
Product Specifications
CAS Number
211555-05-4
Product Name Alternative
WHI-P-97 | WHI P97
Field of Research
Epigenetics & Chromatin
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
OC1=C (Br) C=C (NC2=C3C=C (OC) C (OC) =CC3=NC=N2) C=C1Br
Molecular Formula
C16H13Br2N3O3
Molecular Weight
455.1007
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Phenol, 2,6-dibromo-4-[ (6,7-dimethoxy-4-quinazolinyl) amino]-
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