Purvalanol A
A potent, cell-permeable, selective inhibitor of CDK with IC50s of 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively; also inhibits Saccharomyces cerevisiae Cdc28p (IC50=80 nM) and has no effect on PKC, Raf, CK1, CK2.
Product Specifications
CAS Number
212844-53-6
Product Name Alternative
NG-60 | NG 60 | NG60
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
CC (C) [C@@H] (NC1=NC (NC2=CC=CC (Cl) =C2) =C3N=CN (C (C) C) C3=N1) CO
Molecular Formula
C19H25ClN6O
Molecular Weight
388.8944
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1-Butanol, 2-[[6-[ (3-chlorophenyl) amino]-9- (1-methylethyl) -9H-purin-2-yl]amino]-3-methyl-, (2R) -
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