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HSP27 inhibitor J2

HSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27, induces significant abnormal HSP27 dimer formation in cancer cells; enhances cancer cell sensitization with cisplatin, cisplatin-induced lung cancer cell growth inhibition in vitro; significantly inhibits immune cell infiltration in lung tissue, attenuates radiation-induced pulmonary inflammation in mice.

Product Specifications

CAS Number

2133499-85-9

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 20 mg/mL (75.67 mM)

Smiles

O=C1C=C (C) OC2=C1C (O) =CC (OCC3SC3) =C2

Molecular Formula

C13H12O4S

Molecular Weight

264.295

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

5-hydroxy-2-methyl-7- (thiiran-2-ylmethoxy) -4H-chromen-4-one

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