ABBV-744
ABBV-744 (ABBV744) is a potent, BDII-selective BET bromodomain inhibitor, ABBV-744 is a potent, selective inhibitor of the AR transcription activity; induces tumor growth inhibition in LNCaP and MDA-Pca-2b xenograft models.Prostate Cancer Phase 1 Clinical.
Product Specifications
CAS Number
2138861-99-9
Product Name Alternative
ABBV744
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C (C (N1) =CC (C (C2=CC (C (C) (O) C) =CC=C2OC3=C (C) C=C (F) C=C3C) =CN4C) =C1C4=O) NCC
Molecular Formula
C28H30FN3O4
Molecular Weight
491.563
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1H-Pyrrolo[2,3-c]pyridine-2-carboxamide, N-ethyl-4-[2- (4-fluoro-2,6-dimethylphenoxy) -5- (1-hydroxy-1-methylethyl) phenyl]-6,7-dihydro-6-methyl-7-oxo-
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