PD173074
PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src.
Product Specifications
CAS Number
219580-11-7
Product Name Alternative
PD173074 | PD 173074 | PD-173074
Purity
>98% (HPLC)
Solubility
Ethanol: 100 mg/mL (190.95 mM) ; DMSO: 100 mg/mL (190.95 mM)
Smiles
O=C (NC1=NC2=NC (NCCCCN (CC) CC) =NC=C2C=C1C3=CC (OC) =CC (OC) =C3) NC (C) (C) C
Molecular Formula
C28H41N7O3
Molecular Weight
523.67
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1- (tert-butyl) -3- (2- ((4- (diethylamino) butyl) amino) -6- (3,5-dimethoxyphenyl) pyrido[2,3-d]pyrimidin-7-yl) urea
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