Oridonin
Oridonin is an active diterpenoid compound isolated from the plant Rabdosia Rrubescens, has various pharmacological activities, including antioxidant, anti-tumor capacities and anti-inflammation; inhibits AKT kinase activity (AKT1 and AKT2 IC50=8.4 and 8.9 uM) and interacts with the ATP-binding pocket of AKT, inhibits growth of ESCC in vitro and patient derived xenografts in vivo; inhibits vascular inflammation by blocking NF-κB and MAPK activation.
Product Specifications
CAS Number
28957-04-2
Product Name Alternative
NSC 250682
Purity
>98% (HPLC)
Solubility
Ethanol: 28 mg/mL (76.83 mM) ; DMSO: 72 mg/mL (197.57 mM) ; Water: <1 mg/mL (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
C=C ([C@H] (CC1) [C@H]2O) C ([C@@]32[C@]4 (O) [C@@H] (O) [C@]5 ([H]) C (C) (C) CC[C@H] (O) [C@@]5 (CO4) [C@@]31[H]) =O
Molecular Formula
C20H28O6
Molecular Weight
364.438
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Kaur-16-en-15-one, 7a,20-epoxy-1a,6b,7,14-tetrahydroxy-, (14R) - (8CI)
Available Sizes
Frequently Asked Questions
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