Allopurinol
Allopurinol (Zyloprim) is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM. (In Vitro) :Allopurinol (0, 10, 100, 1000 μg/ml; 17 h) decreases the expression of HIF-1α and HIF-2α protein in HFF and HUVEC cells.Allopurinol (0, 10, 100, 1000 μg/ml; 24 h) reduces angiogenesis traits of HUVEC cells. (In Vivo) :Allopurinol (39 mg/kg; p.o.; daily for 21 successive days) shows anti-depressant activity in mouse.Allopurinol (10-400 mg/kg; i.p.) induces anti-nociception activity in mouse.
Product Specifications
CAS Number
315-30-0
Product Name Alternative
Allopurinol | Zyloprim | Lopurin | Zyloric | Allohexal | Allohexan
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 3 mg/mL (22.04 mM) ; Water: 4 mg/mL (29.38 mM) ; DMSO: 27 mg/mL (198.36 mM)
Smiles
C1=C2C (=NC=NC2=O) NN1
Molecular Formula
C5H4N4O
Molecular Weight
136.11
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1,2-dihydropyrazolo[3,4-d]pyrimidin-4-one
Available Sizes
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