NBD-557
A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; inhibits the fusion between HIV-1NL4-3-luc pseudotyped virus expressing HIV-1HXB2 (X4-tropic) envelope and U87-T4-CXCR4 cells with IC50 of 9.7 uM; inhibits the laboratory-adapted HIV-1 strains IIIB, MN, and V32 with IC50 of 5-16 uM.HIV Infection Preclinical.
Product Specifications
CAS Number
333352-59-3
Product Name Alternative
NBD 557 | NBD557
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (NC1=CC=C (Br) C=C1) C (NC2CC (C) (C) NC (C) (C) C2) =O
Molecular Formula
C17H24BrN3O2
Molecular Weight
382.2953
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Ethanediamide, N- (4-bromophenyl) -N'- (2,2,6,6-tetramethyl-4-piperidinyl) - (9CI)
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